The Baton Rouge District of the Louisiana Conference of the United Methodist Church originated through the 1971 merger of Louisiana’s two racially segregated conferences. From 1968 to 1971, Louisiana’s Conference A (for white churches) and Conference B (for black churches) existed as a temporary measure to work towards racial integration of the Louisiana Conference following the denomination’s 1968 dissolution of the Central Jurisdiction (a racially segregated unit for black Methodists).

In 1972, the district reported 20,841 members. The district consisted of congregations in southeast Louisiana stretching from Tunica (north) to Napoleonville (south) and Saint Francisville (west) to Denham Springs (east).

In 1977, the Baton Rouge District of the Louisiana Conference of the United Methodist Church was dissolved. The congregations that constituted the district were assigned to other districts: Baton Rouge/Hammond District of the Louisiana Conference of the United Methodist Church, Baton Rouge/Lafayette District of the Louisiana Conference of the United Methodist Church, and the New Orleans/Houma District of the Louisiana Conference of the United Methodist Church.

In 1989, the Baton Rouge District of the Louisiana Conference of the United Methodist Church was reestablished following the dissolution of the Baton Rouge/Hammond District of the Louisiana Conference of the United Methodist Church and the Baton Rouge/Lafayette District of the Louisiana Conference of the United Methodist Church.